Renal stone
Conditions
Interventions
two groups:Shi Wei, 7 days, versus placebo
Sponsors
Division of Urology, Department of Surgery, The Chinese University of Hong Kong
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Male patients (age 30-70 years, body weight 55-80 kg) either have recurrent stone disease or new stone former; 2. They are idiopathic stone-formers (includes calcium oxalate, calcium phosphate and uric acid) that is, without underlying urological anomalies such as, medullar sponge kidney, gastrointestinal disorders, hyperparathyroidism or other hypercalcemic disorders, sarcoidosis, Paget's disease, renal tubular acidosis, primary hyperoxaluria, gout or other hyperuricemic disorders, or drugs inducing nephrolithiasis.
Exclusion criteria
Exclusion criteria: 1. Patient with active urinary infection, obstruction or hematuria during the study period; 2. Change of any medication for other medical diseases during the study period; 3. Abnormal renal function (Serum creatinine levels that are more than 1.5 times upper limit of normal range, UML.); 4. Abnormal liver function (ALT > 1.5*UNL associated with alkaline phosphatase >2.5*UNL are not eligible for the study).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effects of Shi Wei on the biochemistry of early morning urine in idiopathic calcium renal stone formers.; | — |
Secondary
| Measure | Time frame |
|---|---|
| The effects of Shi Wei on quantity, size and aggregation of stone crystals in vivo by image analysis.; | — |
Countries
China
Contacts
Public ContactNg Chi Fai
Outcome results
None listed