Childhood Obstructive Sleep Apnoea
Conditions
Interventions
Two groups:Nasonex 4 months versus placebo. The appearance and smell of the corticosteroids and placebo are indistinguishable
Sponsors
Department of Paediatrics, The Chinese University of Hong Kong
Eligibility
Sex/Gender
Male
Age
6 Years to 18 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Once the subjects have completed the overnight PSG, they will be invited to participate in this current study if they satisfied the followings: (1) Confirmed OSAS with a respiratory disturbance index (RDI) of between 1 and 10. It is our current practice to offer children with moderate-severe OSAS (RDI > 10) surgical intervention in the form of adeno-tonsillectomy; (2) Informed consent obtained from parents.
Exclusion criteria
Exclusion criteria: Exclusion criteria: (1) Children with genetic syndromes, congenital or acquired neurological diseases, neuromuscular diseases, and those who have had previous upper airway surgery; (2) Children with fixed nasal obstruction such as previous nasal fracture or deviated nasal septum.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the change from baseline the various respiratory parameters as documented by overnight polysomnography after a 4-month treatment.; | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome is the change from baseline the adenoidal size as assessed by standardized lateral neck radiograph after a 4-month treatment.; | — |
Countries
China
Contacts
Public ContactAlbert Martin Li
Outcome results
None listed