Ischemic Stroke
Conditions
Interventions
Two groups:External Counterpulsation 35 one- hour sessions over a 7 week period
Sponsors
Division of Neurology, Department of Medicine& Therapeutics, CUHK
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1. Patient is 18 or above; 2. Clinical evidence of cerebral infarct or transient ischaemic attack in preceding 6 months with relevant large artery occlusive disease at MRA examination; 3. Modified Rankin score (mRS) =3; 4. Normal platelet count and coagulation profile; 5. Signed informed consent.
Exclusion criteria
Exclusion criteria: Exclusion Criteria: 1. Any medical condition that would not allow the patient to adhere to the protocol or complete the study; 2. Patients with hemorrhagic diathesis, concurrent anti-coagulation treatment, or history of primary intracranial hemorrhage; 3. Other non-ischemic intra-cerebral pathology, e.g. brain tumor, vascular malformation, etc.; 4. Clinical evidence of arrhythmias, significant valvular heart disease on echocardiography, or aortic dissection; 5. Thrombophlebitis, ulcers or chronic skin infection of the lower limbs; 6. Clinical evidence of active malignancy; 7. Patients with pre-proliferative, or proliferative diabetic retinopathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change in NIHSS and cerebral blood Flow(CVIQ) at end of week 7 and 14; | — |
Secondary
| Measure | Time frame |
|---|---|
| recurrent stroke Percentage of patients with favorable outcome (mRS=, Barthel Index) at end of week 7 and 14; | — |
Countries
China
Contacts
Public ContactDr. Ka Sing Wong
Outcome results
None listed