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Single dose Aprepitant to Prevent Postoperative Nausea and Vomiting

Single dose Aprepitant to Prevent Postoperative Nausea and Vomiting

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-09000671
Enrollment
Unknown
Registered
2005-11-16
Start date
2005-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

Two groups:Aprepitant versus placebo

Sponsors

Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: All women undergoing open gynecologic surgery will be eligible if they: (1) are aged between 18 and 60 years; (2) are American Society of Anesthesiologists physical status 1-2.

Exclusion criteria

Exclusion criteria: Exclusion criteria: (1) Patients had preexisting nausea or vomiting; (2) Patients had received opioids or drugs with known antiemetic properties in the 24 hours before surgery; (3) Pregnant patients.

Design outcomes

Primary

MeasureTime frame
Complete treatment response (i.e. no vomiting, no nausea and no need for rescue antiemetics);—

Secondary

MeasureTime frame
Patient satisfaction and quality of reciovery;—

Countries

China

Contacts

Public ContactMatthew Chan
mtvchan@cuhk.edu.hk+853 26322736

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026