A randomised controlled trial to compare the clinical outcomes of needle revision of trabeculectomy bleb vs repeat trabeculectomy in managing failed trabeculectomy.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-09000647

Enrollment

Unknown

Registered

2005-09-09

Start date

2005-03-24

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases

Interventions

Two groups:needle revision of trabeculectomy bleb 30 minutes versus repeat trabeculectomy

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Eye with failed bleb after one single trabeculectomy or after one single trabeculectomy with phacoemulsification; 2. Patients with follow up at least 3 months after the index surgery; 3. Definition of failed trabeculectomy: a. IOP>22mmHg on maximum tolerable anti-glaucoma drugs; b. Fibrotic or scarred bleb with IOP higher than the target pressure for the patient. 4. Patients able and willing to give informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria; 1. Single functional eye; 2. Patients with previous glaucoma operations, including more than one trabeculectomy, needling, glaucoma drainage device or cyclophotocoagulation procedures; 3. Patients refusing needling or trabeculectomy; 4. Patients unable to attend regular follow-up.

Design outcomes

Primary

Measure	Time frame
a. IOP reduction in intraocular pressure by 2 criteria (30% reduction) b. number of IOP-lowering medications;	—

Secondary

Measure	Time frame
a. complications of treatment b. progression of disc changes and/or visual field loss c. need of subsequent surgical intervention;	—

Countries

China

Contacts

Public ContactProf. Clement CY Tham

www.na@163.com+852 2762 3196

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026