Skip to content

Phaco-trabeculectomy with intra-bleb injection of triamcinolone acetonide versus phaco-trabeculectomy with mitomycin C in patients with co-existing cataract and glaucoma – a randomized controlled tria

Phaco-trabeculectomy with intra-bleb injection of triamcinolone acetonide versus phaco-trabeculectomy with mitomycin C in patients with co-existing cataract and glaucoma - a randomized controlled tria

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-09000644
Enrollment
Unknown
Registered
2005-09-08
Start date
2005-05-11
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eye Diseases

Interventions

Two groups:intra-bleb injection of triamcinolone acetonide 1 minute versus mitomycin C

Sponsors

None listed

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Inclusion Criteria 1. Eyes with visually significant cataract and glaucoma indicated phaco-trabeculectomy 2. Risk factors for filtration failure present. These include: ? Conjunctival hyperemia caused by prolonged use of glaucoma eye drops; ? Age <= 50 ? Secondary glaucomas, in particular: uveitic glaucoma ? Surgery requiring uveal manipulation, such as posterior synechialysis or pupil stretching 3. Patient able and willing to give informed consent to participation in the study, and to phaco-trabeculectomy with MMC or IBTA.

Exclusion criteria

Exclusion criteria: Exclusion criteria 1. Single functional eye 2. Previous intraocular surgery, with the exception of laser peripheral iridotomy and argon laser peripheral iridoplasty (ALPI).

Design outcomes

Primary

MeasureTime frame
VA IOP;

Secondary

MeasureTime frame
1. Number of IOP-lowering medications 2. Change in visual field by automated perimetry (Humphrey's) 3. Change in cup-to-disc ratio of the optic nerve head 4. Rate of aqueous outflow by pneumatonometer measurements (in UCH-recruited patient) 5. Anterior segment inflammation 6. Bleb morphology 7. Complications;

Countries

China

Contacts

Public ContactProf. Clement CY Tham
www.na@163.com+852 2762 3196

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026