Nervous System Diseases
Conditions
Interventions
Two groups:Curcumin and ginkgo extract 6 months versus placebo
Sponsors
The Chinese University of Hong Kong
Eligibility
Sex/Gender
Male
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion: Possible or probable AD.
Exclusion criteria
Exclusion criteria: Exclusion: Anticoagulant or antiplatelet treatment or bleeding risk factors; currently smoking; or other severe illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Setting up formulation, patient recruitment, and assay procedures at 0, 1, and 6 months, in preparation for a later clinical trial testing the effectiveness of curcumin and ginkgo in slowing AD progression.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in biochemical measures of AD: Plasma isoprostane and A-beta levels at 1 and 6 months.;Change in cognitive measures of AD: MMSE at 6 months.;Change in others: cholesterol, lipid, C reactive protein, and metal levels in serum at 1 and 6 months.;Curcumin and metabolites at 1 month.; | — |
Countries
China
Contacts
Public ContactLarry Baum
Outcome results
None listed