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Effect of N-Acetylcysteine on heroin craving in heroin addicts

Effect of N-Acetylcysteine on heroin craving in heroin addicts

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-09000605
Enrollment
Unknown
Registered
2009-12-03
Start date
2009-12-05
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heroin addiction

Interventions

group A:N-Acetylcysteine
group B:Capsule filled with amylum

Sponsors

Ningbo Addiction Research and Treatment Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 55 years old, male or female; 2. Diagnosis is based on the DSM-IV - opioid dependence diagnostic criteria; 3. After 10-day acute detoxification; 4. Nomal physical and laboratory examination; 5. Negative urinary test for morphine; 6. To be able to and willing to provide signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Allergy to medicine (including scopolamine,chlorpromazine and methadone); 2. Serious nervous diseases and mental disorders; 3. Poly-drug abuse ( more than 1 time per month); 4. Currently participating in other clinical trials; 5. Poor compliance, can not be in line with the interview.

Design outcomes

Primary

MeasureTime frame
Cue induced craving score;Craving score;

Secondary

MeasureTime frame
SAS score;

Countries

China

Contacts

Public ContactWenhua Zhou
lskingcn@yahoo.com.cn+86 574 87145142

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026