Paroxysmal atrial fibrillation
Conditions
Interventions
Group A:Circumstantial pulmonary vein isolation(CPVI)
Group B:CPVI + re-isolation guided by ATP-induction postisolation
Group C:CPVI + re-isolation guided by 30min of waiting period postisolation
Group D:CPVI + re-isolation guided by 30min of waiting period and ATP-induction postisolation
Sponsors
SIR RUN RUN SHAW Hospital of Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Symptomatic paroxysmal AF; 2. Drug refractory; 3. Aged 18-75 yrs; 4. Able and willing to provide signed informed consent (at least 3 months).
Exclusion criteria
Exclusion criteria: 1. Reversible causes of atrial fibrillation; 2. Postoperative atrial fibrillation; 3. Previous left atrial ablation; 4. A documented intraatrial thrombus, tumor, or other abnormality that precludes catheter placement; 5. A contraindication to antiarrhythmic medicine, anticoagulation, adenosine or isoproterenol, Severe pulmonary disease; 6. Cardiac surgery, myocardial infarction, or percutaneous coronary intervention within the previous 3 months; 7. A life expectancy of 2 years or less; 8. A high probability of undergoing cardiac transplantation within the next 12 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of freedom form atrial fibrillation post-CPVI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Left atrium size;Left ventricular ejection fraction;Left ventricular diastolic diameter; | — |
Countries
China
Contacts
Public ContactChenyang Jiang
Outcome results
None listed