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A Pilot Clinical Study of Olfactory Mucosa Autografts in Human Spinal Cord Injury

A Pilot Clinical Study of Olfactory Mucosa Autografts in Human Spinal Cord Injury

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-09000482
Enrollment
Unknown
Registered
2009-07-23
Start date
2009-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal cord injury

Interventions

A:Laminectomy+Scar lysis+transplantation of the olfactory mucosa
B:Laminectomy+Scar lysis

Sponsors

Second Affiliated Hospital of Wenzhou Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Male and female aged 18 to 55 years old who suffered a SCI more than 6 months previouslyand were chronically paraplegic or tetraplegic; 2. The inclusion criteria were grade A on the ASIA Impairment Scale; 3. presence of thoracic or lumbar spinal cord lesion and the lesion should smaller than 5 cm; 4. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Presence of significant nasal and paranasal sinus pathology; 2. Presence of an additional serious medical problem (e.g. carcinoma, auto-immune disease, diabetes mellitus); 3. Syringomyelia; 4. Spinal vertebral instability; 5. Substance abuse or patients with major and current psychiatric illness.

Design outcomes

Primary

MeasureTime frame
ASIA Scores;

Secondary

MeasureTime frame
MRI EMG Urodynamic studies;

Countries

China

Contacts

Public ContactHuazi Xu
spinexu@163.com+86 13616632111

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026