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Clinical Trail of CRRT Combined with Blood Absorption for MODS

Clinical Trail of CRRT Combined with Blood Absorption for MODS

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-09000430
Enrollment
Unknown
Registered
2009-05-13
Start date
2009-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Organs Dysfunction Syndrome

Interventions

A:CRRT
B:CRRT combined with blood absorption

Sponsors

Department of nephrology, West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. With the diagnosis of MODS in accordance with the standard diagnostic criteria (dysfunction of more than 2 organs); 2. With the diagnosis of SIRS or sepsis in accordance with the standard diagnostic criteria.

Exclusion criteria

Exclusion criteria: 1. HIV infection; 2. Pregnancy, organ transplantation recipient within 1 year or cachexia; 3. Allergy of cardiopulmonary circulation,anticoagulant or blood purification equipments; 4. Cannot undergo blood purification treatment because of other diseases or having severe complications during treatment; 5. Patients having other diseases which may influence the outcome, eg.rheumatic diseases,severe autoimmune diseases; 6. Cannot cooperate effectively during treatment; 7. Involved in other clinical trails; 8. Considered not suitable for the trail by doctors(at least 2 attendings)

Design outcomes

Primary

MeasureTime frame
vital signs;cytokines (TNF-alpha, IL-1 beta, IL -6, IL-10);APACHE score;mortality;rennal function;adverse reaction;

Secondary

MeasureTime frame
short-term mortality;

Countries

China

Contacts

Public ContactPing Fu, Ling Zhang
fupinghx@163.com+86 28 81812201

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026