Effect of haloperidol on early postoperative delirium and late postoperative outcomes in elderly patients after non-cardiac surgery: a multi-central, randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-09000379

Enrollment

Unknown

Registered

2009-04-29

Start date

2009-05-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients admitted to the SICU after major non-cardiac (intra-thoracic or intra-abdominal) surgery under general anesthesia.

Interventions

Group A:Haloperidol is administrated (IV bolus 0.5mg followed by continuously IV infusion 0.1mg/h) until 24 hours after surgery.

Group B:Normal saline is administrated intravenously in the same rate and volume as that in Group A.

Eligibility

Sex/Gender

All

Age

65 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Age >= 65 years; (2) Patients admitted to the SICU after major non-cardiac (intra-thoracic or intra-abdominal) surgery under general anesthesia.

Exclusion criteria

Exclusion criteria: (1) Rejection to participate in the study; (2) Previous psychiatric diseases; (3) Preoperative coma; (4) Neurosurgery; (5) Individuals unlikely to survive for more than 24 h.

Design outcomes

Primary

Measure	Time frame
the incidence of early postoperative delirium;Mortality;	—

Secondary

Measure	Time frame
Incidence of postoperative complications;	—

Countries

China

Contacts

Public ContactDongxin WANG

wangdongxin@hotmail.com+86 13910731903

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026