A Prospective Randomized Trial Comparing Percutaneous Local Ablative Therapy and Partial Hepatectomy for Small Hepatocellular Carcinoma according with Milan Criteria

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-09000372

Enrollment

Unknown

Registered

2009-04-10

Start date

2003-03-11

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

radiofrenquency ablation gruop:radiofrenquency ablation

resection gruop:partial hepatectomy

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1. diagnosis of HCC was confirmed; 2. single lesion less than 5 cm in diameter, or 3 or fewer lesions, each 3cm or less in diameter; 3. no extrahepatic metastasis or vascular invasion; 4. liver function of Pugh-Child Class A or B; 5. no previous or simultaneous malignancies; 6. indocyanine green retention at 15 minutes (ICG-R15) 50*10^9/L or correctable by platelet transfusion, a prothrombin time prolongation of less than 5 seconds; 8. absence of refractory ascites; 9. no previous treatment of HCC.

Exclusion criteria

Exclusion criteria: 1. patient who is not suitable to be treated by both surgical resection and RFA; 2. patient who is not living in local province(hard to follow up); 3. patient who is willing to accept liver transplantation.

Design outcomes

Primary

Measure	Time frame
overall survival;	—

Secondary

Measure	Time frame
recurrence;recurrence-free survival;	—

Countries

China

Contacts

Public ContactZeng Yong

zengyong@medmail.com.cn+86 028 81812472

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026