cough of post infectious disease
Conditions
Interventions
A:TCM granule
Sponsors
Guangdong Provincial Hospital of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Had ever stuffy nose, runny nose, sneezing, tears, pharyngodynia, cough, sputum, fever and other symptoms of upper respiratory tract infection, persistent cough after infectious symptoms resolving, manifested as irritating dry cough or expectorate a small amount of white sputum; acute tracheo-bronchitis induced by acute upper respiratory tract infection, manifested as expectorate yellow purulent sputum or yellow-white viscous sputum, but infectious symptom has relieved as including; cough duration is from 3-8 weeks; normal chest film; normal pulmonary ventilation function and bronchial provocation test is negative; the proportion of eosinophils of induced sputum cytology=3; Wind-cold Lingering in Lung or Wind-heat Stasis in Lung according to differentiation of syndrome by TCM; age is from 18-65 years old; informed consent.
Exclusion criteria
Exclusion criteria: History of chronic respiratory diseases like asthma, chronic bronchitis, etc; history of chronic heart failure or serious primary disease of other system; postnatal drip or acid reflux, stomachache and so on in usual; smoking or smoking cessation relapse at present; intake ACEI late month; body temperature higher than 37.3 degree C; peripheral white blood cell count>10*10^9/L or<4*10^9/L; lactation, pregnancy or preparing for pregnancy; psychotic; non-cooperation; participate in other clinical trial late month or at present.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Cough sensitivity, airway neurogenic inflammation mediators, number of cough recurrent, effectivenes;Cough sensitivity and airway neurogenic inflammation mediators only detected in subcenter in Guangzhou area;stool routine and occult blood test, hepatic and renal function, electrocardiogram; | — |
Primary
| Measure | Time frame |
|---|---|
| Scoring of cough, time of cough remission, numeric; | — |
Countries
China
Contacts
Public ContactLin Lin
Outcome results
None listed