Irritable bowel syndrome with diarrhea (IBS-D)
Conditions
Interventions
Control group:Decoction of placebo, 150ml, Tid
Experimental group:Changanyihao Decoction, 150ml,Tid
Sponsors
Xiyuan Hospital Affiliated to China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Fulfill the diagnostic criteria of IBS-D of Rome III criteria; (2) Between 18 years to 70 years; (3) The score of IBS-SSS more than 75; (4) Sign the informed consent and will to accept corresponding intervention; (5)Live locally for some time which can maintain treatment and follow-up, have the ability of reading power.
Exclusion criteria
Exclusion criteria: (1) IBS-C, IBS-M and unsubtyped IBS; (2) Patients accompanied with serious disease of heart, liver, hematopoietic system, etc, or patients with tutor; (3) Patients with structural abnormity of digestive system or systematic disease which can affect bower movements of gastrointestinal tract (such as hyperthyreosis, diabetes, chronic renal insufficiency, psychiatric or nervous system disease); (4) Patients who are in use or will continue to take drugs which may affect function of gastrointestinal tract (such as anticholinergic agents, Ca2+ channel blocker, 5-HT3 receptor antagonist, antidiarrheal, antiacid, prokinetics, antidepressant drug; ntianxietic, microecological modulator of intestinal flora); (5) History of operation on abdominal region, such as ecphyadectomy and cholecystectomy; (6) History of allergy to food and drugs; (7) Pregnant or lactating females; (8) History of psychiatric or nervous system disease; (9) Patients who are in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the character of stool;Adequate relief, AR;IBS-SSS; | — |
Secondary
| Measure | Time frame |
|---|---|
| HAD;IBS-QOL;Improvement of syndromes of Traditional Chinese medicine; | — |
Countries
China
Contacts
Public ContactXudong Tang
Outcome results
None listed