Depression
Conditions
Interventions
Two groups:Pharmacist education versus usual care
Sponsors
None listed
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Adult patients, who are newly diagnosed with depressive disorders, able to communicate in Cantonese or English, have no previous exposure (within the past six months) to any antidepressants, and will start a treatment with an antidepressant, will be included.
Exclusion criteria
Exclusion criteria: 1. have dementia or any kinds of significant cognitive impairment, hearing impairment, terminal illnesses, psychosis, bipolar disorder, history of alcohol or any kinds of substance abuse; 2. have high suicidal risks, and 3. are pregnant or nursing, illiterate, taking St John's Wort or any other Traditional Chinese Medicines (TCM) for depression
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of patients with at least 50% improvement in the Chinese version of 13-item Beck Depression Inventory (BDI) score Percentage of patients with Hamilton Depression score (HAM-D) < or =7; | — |
Secondary
| Measure | Time frame |
|---|---|
| The average change in BDI score at 6-month compared to that in baseline;The improvement in health-related quality of life assessed by The Chinese (Hong Kong) SF-36 at baseline and 6-month The baseline and 6-month Clinical Global Impression-Severity of Illness (CGI-S) and Improvement (CGI-I) scales Percentage of patients who compliant with antidepressant treatment at 3- and 6-month.;Patients who consumed >80% of pills dispensed during the prescribed period will be categorized as compliant with antidepressant treatment Cost-utility analyses to estimate the ratio between the cost of intervention and the potentialbenefit in symptom improvement observed; | — |
Countries
China
Contacts
Public ContactLee Chui Ping
Outcome results
None listed