phacoemulsification cystoid macular edema
Conditions
Interventions
Two groups:Tromethamine 0.5% (Acular) eye drop Control group will receive placebo ie. 0.9%normal saline eye drop
Sponsors
None listed
Eligibility
Sex/Gender
Male
Age
51 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Senile cataract in patients older than 50 years old; 2. Adequate fundal view for OCT measurement before cataract surgery; 3. pre-op OCT could be obtained with signal strength 6.0; 4. fully informed consent.
Exclusion criteria
Exclusion criteria: 1. pre-existing macular edema; 2. any conditions known to cause macular edema, including retinal vein or artery occlusion, uveitis, premacular fibrosis, retinitis pigmentosa, macular hole and choroidal neovascularisation; 3. significant ocular diseases such as glaucoma; 4. pre-existing refractive error of >-6.00 diopters or +6.00 diopters; 5. systemic medications that may affect retinal thickening such as steroid or diuretics; 6. single eye patients; 7. For diabetic patients, history of intravitreal or sub-Tenon's capsule injection or triamcinolone acetonide.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Macular thickness and central foveal volume assessed by OCT; | — |
Secondary
| Measure | Time frame |
|---|---|
| 2. Best corrected visual acuity (ETDRS chart) 3. risk factors for development of CME ( e.g. phaco time, phaco energy etc.) 4. development of posterior vitreous detachment; | — |
Countries
China
Contacts
Public ContactProf. Dennis SC Lam
Outcome results
None listed