A Prospective Study to Investigate the Effects of Different Shockwave Delivery Rates in Extracorporeal Shockwave Lithotripsy in Patients Suffer form Renal Calculi

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-08000627

Enrollment

Unknown

Registered

2008-07-15

Start date

2008-08-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal calculi

Interventions

Two groups:Extracorporeal Shockwave Lithotripsy (ESWL) for one week. All patients will be treated with ESWL but at a different shockwave delivery rate among groups.

Eligibility

Sex/Gender

Male

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria are: 1. Adult patient (aged = 18 years old); 2. Solitary radio-opaque renal stones of size 5-20mm in maximal diameter as measured from plain radiography; 3. Clinically decided for primary ESWL

Exclusion criteria

Exclusion criteria: Exclusion criteria are: ?Stones associated with any renal or ureteric anatomical abnormality, such as caliceal diverticulum, horseshoe kidney, ureteropelvic junction obstruction etc; ?Patients with ureteric stent or nephrostomy tube inserted; ?Patients with known history of cystine stone; ?Patients with multiple stones in the same calix; ?Patient with history of allergy or any abnormal reaction alfentanil.

Design outcomes

Primary

Measure	Time frame
Successful treatment ?Defined as either stone free or presence of clinically insignificant residual fragments (less than 4mm) at 12 weeks after one session of lithotripsy. ?This will be assessed by plain radiography and non-contrast computerized tomogram;	—

Secondary

Measure	Time frame
?Degree of renal injury o The changes in the urine level (compared to pre-SWL level) of NAG, HA, NGAL and IL-18 of the two groups (different shockwave delivery rates) will be assessed;?Response of patients to the treatment o The following factors will be assessed and then compared between the two groups Maximal Pain score;- Pain intensity verbal rating scale tool [8] will be used to assess the severity of pain at every 1000 shocks and at the end of treatment Analgesics consumption;- the amount of additional usage of analgesics delivered by PCA will be recorded at the end of treatment.;	—

Measure

Time frame

?Degree of renal injury o The changes in the urine level (compared to pre-SWL level) of NAG, HA, NGAL and IL-18 of the two groups (different shockwave delivery rates) will be assessed;?Response of patients to the treatment o The following factors will be assessed and then compared between the two groups Maximal Pain score;- Pain intensity verbal rating scale tool [8] will be used to assess the severity of pain at every 1000 shocks and at the end of treatment Analgesics consumption;- the amount of additional usage of analgesics delivered by PCA will be recorded at the end of treatment.;

—

Countries

China

Contacts

Public ContactNg Chi Fai

ngcf@surgery.cuhk.edu.hk+852 26322625/ 26323953

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026