Chronic obstructive pulmonary disease (COPD)
Conditions
Interventions
Group A:Routine drug inhalation atomized by mixture of air and oxygen
Group B:Drug inhalation atomized by variant partial ratio of heliox, and the samples come from group A
Sponsors
PLA General Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients in ordinary endemic area of respiratory disease; 2. fit the definition of COPD set by GOLD 2006, and accord with the definition based on medical record, physical examination, and sternite; 3. Mind distinctness, to be able to match; 4. Vital sign steady; 5. No other organ apparent functional insufficiency (such as heart, liver and kidney, ect.)
Exclusion criteria
Exclusion criteria: 1. Refuse the use of heliox for treating; 2. pH <7.30; 3. Mind abstacle, Glasgow score<8; 4. Other organ functional insufficiency(such as heart, liver and kidney, ect) 5. Septic shock; 6. Apnoea; 7. Unable to match or unsuitable for veil.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SpO2 (%), pH, PaO2 (mmHg), PaCO2 (mmHg), HCO3- (mmol/L), FVC(ml), FEV1(ml), FEV1%, PEF(ml), FRC(ml); | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory rate, cardioverter, dyspnea score, assistant respiratory acting score; | — |
Countries
China
Contacts
Public ContactXie Lixin
Outcome results
None listed