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A randomized controlled trial of Huangqi injection in the treatment of patients with acute decompensate chronic heart failure and deficiency of vital energy

A randomized controlled trial of Huangqi injection in patients with acute decompensate chronic heart failure and deficiency of vital energy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-08000257
Enrollment
Unknown
Registered
2008-11-17
Start date
2008-06-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute decompensate chronic heart failure

Interventions

Group A:Huangqi injection
Group B:5% glucose injection

Sponsors

Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years; 2. ADCHF patients, heart function NYHA III-IV; 3. The main symptom is decomposition; 4. LVEF<=40% is proved by ultrasonic cardiogram; 5. Elevator blood BNP (Brain Natriuretic Peptide); 5. Informed written consent was obtained from every participant before data collection; 6. with deficiency of vital energy.

Exclusion criteria

Exclusion criteria: 1. severe arrhythmia: degree II type II atrioventricular block or degree III atrioventricular block, ventricular tachycardia, sick sinus syndrome, frequent supraventricular tachycardia; (exclude patients after cadiac pacing therapy); 2. hypertrophic cardiomyopathy, restrictive cardiomyopathy, infective endoarditis, hyponutrition cardiomyopathy, pericardial tamponade, acute myocarditis, arcula cordis diseases; 3. acute myocardial infarction diagnosed in one week; 4. severe primary lung diseases (such as ARDS, COPD, pulmonary embolism, or pulmonale etc.); 5. other severe uncontrolled diseases of different systems; 6. alergy to investigational drug or never used investigational drug and with history of hyperacuity; 7. with severe mental sickness; 8. children, pregnant and breast feeding period woman.

Design outcomes

Primary

MeasureTime frame
Tei index by UCG; LVEF by UCG; BNP; etc.;

Countries

China

Contacts

Public ContactHuicong Xu
xxuhuicong@163.com+86 0 13826281978

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026