liver cirrhosis
Conditions
Interventions
Control group:Patients has gastroscopy to investigate the degree of gastric fundus varices
Histoacryl blue injection was performed using an Olympus electronic gastroscope and a disposable injection needle. Each shot contained 0.5ml Histoacryl and 0.5ml Lipiodol. Last the needles were rinsed
Experimental group:The included patients was performed PTVE by venipuncture, intubation tube, visualization, histoacryl was then injected continuously until all the gastric fundus varices and opacifie
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
47 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Cirrhotic patients with acute or recent (within 3 months) gastric variceal hemorrhage; 2. Cirrhotic patients was confirmed with the clinical and image data; 3. The degree of gastric varices was confirmed by gastroendoscopy in these patients; 4. Computerized tomography (CT) portal venography was performed for detection of variceal afferent veins before operation; 5. Giving the consent to complete preoperative check and postoperative recheck.
Exclusion criteria
Exclusion criteria: 1. Association with the contraindication such as esophageal stenosis for gastroscopy or has grave esophagitis; 2. Had previous endoscopic, surgical treatment or transjugular intrahepatic portal systemic shunt for gastroesophageal variceal bleeding; 3. Grave hypertension, coronary heart disease, or impaired function of cardiorespiratory. 4. Association with hepatocellular carcinoma or other malignancy; 5. Complete obstruction of the portal vein due to thrombosis; 6. Encephalopathy greater than stage II; severe jaundice with serum bilirubin more than 100 mg L-1; 7. Presence of hepatorenal syndrome or chronic renal insufficiency; 8. Obvious hemorrhagic tendency, PT>25s; 9. The portal vein was failure to venous cannula with kinds of cause; 10. Inability or refusal to give the consent to complete preoperative check and postoperative recheck.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| UGI rebleeding;Computerized tomography (CT) scanning and 3D recon;survival rate;Arrest of acute bleeding;Gastric Fundus Varices eradication and relaps; | — |
Secondary
| Measure | Time frame |
|---|---|
| The improving of clinical symptom;Liver functional assessment;quality of life;Complication; | — |
Countries
China
Contacts
Public ContactZhang Chunqing
Outcome results
None listed