port-wine stain
Conditions
Interventions
control group:receiving placebo in the first period, hemoporfin in the second period of the study
Treatment group:rreceiving hemoporfin
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Age
14 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients were eligible for study enrolment if they were aged between 14 and 65 years with clinically diagnosed port-wine stain. The therapy area should receive no isotope or photodynamic treatment previously, neither systemic treatment for port-wine stain during the past 4 weeks, nor topical treatment during the past 2 weeks. All patients were given written informed consent before any study-related tests were done. If the patient is younger than 18 years, the guardian's written informed consent was also obtained. Patients were required to have adequate haematological, renal, and hepatic function.
Exclusion criteria
Exclusion criteria: The main exclusion criteria were: Other skin diseases that may interfere with the study evaluation; known to be allergic to porphyrins or its analogues; patients with photosensitivity or porphyria; allergic constitution or scar diathesis; immunocompromised patients; patients with electrocardiographic abnormality or known organic heart disease, coagulation disorders, psychiatric disease or severe endocrinopathy; taken known photosensitizer during the past 1 month; pregnancy or lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| third party assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Investigators' subjective assessment;Patients' subjective assessment; | — |
Countries
China
Contacts
Public ContactZhu Xue-jun
Outcome results
None listed