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A randomized, single blind controlled trial: interference therapy of temporarily obstruct arterial blood flow and augment pressure perfusion for treating liver cancer

A randomized, single blind controlled trial: interference therapy of temporarily obstruct arterial blood flow and augment pressure perfusion for treating liver cancer

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-08000196
Enrollment
Unknown
Registered
2008-11-23
Start date
2008-10-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Original liver cancer

Interventions

Group 1:Poor blood supply control group
Group 4:Moderate blood supply experimental group
Group 3:Moderate blood supply control group
Group 2:Poor blood supply experimental group: using general conduit+saccule conduit+pressure pump

Sponsors

The Eastern Hepatic Surgery Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Important organises includes heart, brain, lung, etc, to be able to tolerable operation; 2. Total diameter of the tumours should be 3~15 cm, number of tumours equal or less than 5, confirmed by CT or MRI; 3. Liver function (Child grade) grading higher than B (include B); 4. Expecting survival should be longer than 6 months.

Exclusion criteria

Exclusion criteria: 1. Irritability for iodine; 2. Received other chemotherapy or obstruct therapy; 3. Received other TACE, radiotherapy or biotherapy in last 30 days; 4. Disseminated liver cancer, jaundice caused by main vessel of portal vein or bile duct cancer embolus (total bilirubin high than 51 umol/L).

Design outcomes

Primary

MeasureTime frame
MRI ADC value of tumour and liver substance area;Iodine oil filled area, measured by CT;Partial remission, entirely remission, stable and progress of illness;

Secondary

MeasureTime frame
AFP, CA19-9;

Countries

China

Contacts

Public ContactHongyan Chen
Chengys9304@yahoo.com.cn+86 021 25070861

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026