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A randomized controlled trial of treatment of portal vein tumor thrombus after hepatocellular carcinoma resection

A randomized controlled trial of treatment of portal vein tumor thrombus after hepatocellular carcinoma resection

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-08000189
Enrollment
Unknown
Registered
2008-12-14
Start date
2005-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Portal vein tumor thrombus after hepatocellular carcinoma resection

Interventions

Group 2:TACE+Laser ablation: One week after TACE, laser ablation is given to the PVTT.
Group 1:TACE: The chemotherapeutic drugs and 2 to 10 ml lipiodol are given via hepatica propria artery. The chemotherapeutic drugs include 5-Fu 1500 mg, epirubicin 30 mg, cisplatin 30 mg.

Sponsors

Shanghai Eastern Hepatobiliary Surgery Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. PVTT after liver resection was diagnosed with at least two types of imaging findings, such as CT, MRI or color doplor findings; 2. The functions of the kidney, heart and lung and the routine test of the blood are in good condition; 3. The liver function is of grade A or B in Child-Pugh classification; 4. The patient is eligible of the trial and will show consent to the test.

Exclusion criteria

Exclusion criteria: 1. any of the parameters. WBC less than 2000/ml, Hb less than 90g/L or PLT less than 50000/ml; 2. disfunction of the heart, lung, kidney, or brain; 3. any other disease might affect the trial or 4. the patients would not sign the consent to the trial.

Design outcomes

Primary

MeasureTime frame
distal metastasis;overall survival;

Secondary

MeasureTime frame
clinical presentation;laboratory findings;the changes of the PVT;

Countries

China

Contacts

Public ContactLu Zhenghua
lu_zhenghua@126.com+86 021 25070736

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026