A clinical study of progesterone for acute craniocerebral injury

A multicenter, randomized double blinding, large scale, placebo controlled, prospective clinical study of progesterone for acute craniocerebral injury

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-08000174

Enrollment

Unknown

Registered

2008-05-30

Start date

2008-10-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute craniocerebral injury

Interventions

Group A:Placebo injection as study group

Group B:immediately muscle injection of progesterone (1mg / kg, Q 12h, for 5 days)

Eligibility

Sex/Gender

All

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: GCS: 5, Age: >15y, <65y; Admission duration: <8h

Exclusion criteria

Exclusion criteria: Used the female hormone medicines within 1 month since onset of the injury; especially severe craniocerebral injury; pregnant women or lactation patients, have the diseases which may affect the assessment of nerval function before injury

Design outcomes

Primary

Measure	Time frame
Mortality;Expanded GCS score;disability rate score;	—

Secondary

Measure	Time frame
MAP;CCP;GCS score;ICP;	—

Countries

China

Contacts

Public ContactGuoming Xiao

gxiao@hznu.edu.cn+86 0571 88303638

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026