Gastric precancerous lesion (gastric epithelial dysplasia of mild or moderate degree at the base of chronic atrophic gastritis)
Conditions
Interventions
Group C:Moluo Dan, 9g, taken orally, Tid
Group A:Folic acid, 5mg, taken orally, Tid
Group B:TCM "Bianzhen", 100-150ml once orally, Tid
Sponsors
Xiyuan Hospital, Chinese Academy of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Outpatient or inpatient fulfilling the diagnosis of gastric precancerous lesion by gastro-endoscopy and histopathology; 2. Fulfilling the traditional Chinese medicine diagnosis of liver-stomach disharmony syndrome, stomach-yin insufficiency syndrome, spleen-stomach damp-heat syndrome, qi stagnation and spleen deficiency syndrome; 3. Age of 18–70, both males and females; 4. With informed written consent.
Exclusion criteria
Exclusion criteria: 1. Gastric epithelial dysplasia of severe degree; 2. Previous history of gastrectomy; 3. Long-term administration of non-steroidal anti-inflammatory drug (NSAIDs); 4. Suggestive of gastric cancer or malignant lesion of other systems; 5. Severe systemic diseases, like cardio-cerebral-vascular disease, hepatic diseases, Blood System Diseases, and etc; 6. Psychosis patient, dementia, intelligence or language disorder incapable of adequatecooperation; 7. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence rate of gastric cancer;Histopathological score of gastric mucos; | — |
Secondary
| Measure | Time frame |
|---|---|
| Mucosal lesion score under endoscopy;Symptom score;Score of Patient reported outcome instrumen; | — |
Countries
China
Contacts
Public ContactXudong Tang
Outcome results
None listed