Adult Kaschin-Beck disease.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with Kashcin-beck disease elder than 40 years without other bone and cartilage correlated diseases, and without the diseases may influence metabolism.
Exclusion criteria
Exclusion criteria: History or active presence of other bone or cartilage disease and an illness known to affect bone metabolism (i.e., Paget's disease, osteoporosis, osteomalacia, cancer or alcoholism); traumatic knee lesions; substantial abnormalities in haematological, hepatic, renal.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Three sulphate unsaturated disaccharides in urine;Hydroxyproline in urine;Pyridinoline level in patients' urine;Mean knee joint-space width; | — |
Countries
China