Hemorrhage post caesarean section, spontaneous delivery and surgical abortion
Conditions
Interventions
Herba Leonuri group:After fetal delivery,firstly, give Herba Leonuri 40mg into uterus by intramuscular injection, then Herba Leonuri 40mg ,q12h for 3 times by intragluteal injection.
Herba Leonuri and Oxytocin group:After fetal delivery, firstly, give Herba Leonuri 40mg and Oxytocin 10IU into uterus by intramuscular injection, then Herba Leonuri 40mg ,q12h for 3 times by intraglut
Oxytocin group:After fetal delivery,firstly, give Oxytocin 10IU into uterus by intramuscular injection and Oxytocin 10IU by intravenous drip, then Oxytocin 10IU ,q12h for 3 times by intragluteal injec
Sponsors
Renji Hospital affiliated to Medical School, Shanghai Jiaotong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients meet the following criteria: 1. for caesarean section parturients: (1) age ranges from 20 to 34 years old; (2) gestational age more than 37 weeks ,less than 42 weeks; (3) underwent caesarean section; (4) agree to join in the trial and sign the informed consent document. 2. for spontaneous delivery parturients: (1) age ranges from 20 to 34 years old; (2) gestational age more than 37 weeks, less than 42 weeks, following vaginal delivery; (3) spontaneous delivery without prolongation of labor time; (4) agree to join in the trial and sign the informed consent document; 3. surgical abortion woman: (1) terminate early pregnancy with surgical abortion; (2) intrauterine gestation diagnosis by uterus ultrasonography, gestational age more than 50 days, less than 70 days; (3) agree to join in the trial and sign the informed consent document.
Exclusion criteria
Exclusion criteria: Patients meet following criteria: 1. For caesarean section and spontaneous delivery parturients: (1) hepatitis or liver dysfunction; (2) accompany with plate reduction or blood coagulation disorder; (3) receive tocolytic therapy 48 hours before operation; (4) placenta previa, placental abruption ormanual removal of placenta; (5) patients refuse to sign the informed consent document. 2. For surgical abortion woman: (1) patients with pregnancy complications; (2) hepatitis or liver dysfunction; (3) accompany with plate reduction or blood coagulation disorder; (4) patients refuse to sign the informed consent document.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vaginal bleeding quantity within 48 hours after operation;Vaginal bleeding quantity within 24 hours after operatoin;Vaginal bleeding quantity within 12 hours after operation;Vaginal bleeding quantity within 2 hours after operation;Vaginal bleeding quantity during operation;Vaginal bleeding quantity within 72 hours after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Supplementary tocolytic drug dosage;Hemoglobin content;Rate of postpartum haemorrhag; | — |
Countries
China
Contacts
Public ContactLin Qide
Outcome results
None listed