Esophageal carcinoma (Stage I and II)
Conditions
Interventions
Group A:video-assisted thoracoscopy surgey
Group B:Routine radical resection
Sponsors
Zhongshan Hospital of Fudan University, Evidence-based medicine center of Fudan
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed pathologically as carcinoma by endoscope biopsy or Cytological examination. Pathological type was squamous carcinoma or adenocarcinoma. UGI barium meal showed length of tumor =12 months; 3. Patients diagnosed pathologically as carcinoma by endoscope biopsy or Cytological examination. Pathological type was squamous carcinoma or adenocarcinoma. UGI barium meal showed length of tumor 4.0*10^9/L, N% 50-70%, platelet >100*10^9/L, Hb>95g/L. Liver function indices: serum bilirubin is lower than 1.5 times of normal maximum level. ALT and AST are lower than 1.5 times of normal maximum level; Lung function: FEV1 >=1.2L, FEV1% >=50% and DLCO >=50%; 4. Patients can understand the trial and voluntarely sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Esophageal carcinoma stage is not stage I (T1N0M0), IIa (T2N0M0?T3N0M0) or IIb(T1-2N1M0); 2. patients have received been receiving Chemotherapy/Radiotherapy/targeted therapy; 3. Patients had other type of tumour (Except cured carcinoma in situ of uterine cervix and basal cell carcinoma); 4. Patients have uncontrolled Diabetes; 5. Patients have abnormal function of heart, Lung, liver and kidney; 6. Patients have sever complications that can not receive operation; 7. Patients have uncontrolled psychiatric disease; 8. Researchers do not think the patients are not suitable to the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| progression-free survival;Overall survival time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life; | — |
Countries
China
Contacts
Public ContactLijie Tan
Outcome results
None listed