Skip to content

Is Albumin Administration Beneficial In Early Stage of Postoperative Hypoalbuminemia Following Gastrointestinal Surgery?: A Prospective Randomized Controlled Trial

Is Albumin Administration Beneficial In Early Stage of Postoperative Hypoalbuminemia Following Gastrointestinal Surgery?: A Prospective Randomized Controlled Trial

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-08000125
Enrollment
Unknown
Registered
2008-05-29
Start date
2007-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointerstinal diseases

Interventions

Control group:Inject 100 ml 0.9% saline daily on day of surgery
Albumin group:Inject 100 ml 20% Albumin daily on day of surgery

Sponsors

Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients who were 18~80 years of age and of either sex; undergoing moderate or major gastrointestinal surgery (including but not limited to radical surgery for gastric cancer, radical surgery for rectal cancer and colonic cancer, distal partial pancreatectomy, etc); the preoperative plasma albumin concentration >=3.5 g/dL, hemoglobin >=9.0 g/dL; the liver function was Child A or B; the intraoperative blood loss was no more than 2000ml; with a plasma albumin concentration <3.0 g/dL after operation; patients should be able to understand study procedures and were willing to participate in the study.

Exclusion criteria

Exclusion criteria: Patients who were allergic to albumin; 24-hour urine <500ml; patients who’re suffering from volume overload-induced pulmonary edema; patients being pregnant, lactating, preparing to be pregnant or lactating during the study

Design outcomes

Primary

MeasureTime frame
Mortality;Complications;Serum Alb, total protein, pre-albumi;

Secondary

MeasureTime frame
Duration of hospitalization after operatio;

Countries

China

Contacts

Public ContactYulong He
ylh@medmail.com.cn+86 020 87331059

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026