Advanced nasopharyngeal carcinoma
Conditions
Interventions
GTRT:In the GTRT group, Gendicine 1*10^12 virus particle
RT:In the GTRT group, Gendicine 1*10^12 virus particle
Sponsors
Beijing Cancer Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients should be 18 to 80 years old. The patients were clinically staged according to the fifth edition of the International Union Against Cancer (UICC) TNM staging systems (1997). Initial treatment with radiotherapy was judged to be the accepted standard of care. Patients must have a projected life expectancy of at least 6 months and a Karnofsky performance score of at least 70%. Patients were required to have adequate bone marrow function (WBC count 4.0*10^9/L, hemoglobin 7g/L, platelet count 70*10^9/L) and adequate liver and renal function (AST, ALT, BUN and Cr < 1.5 time the upper limit of normal).
Exclusion criteria
Exclusion criteria: Pregnant or nursing women, patients with uncontrolled serious infections, or with serious heart and lung failure were excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local-regional recurrence;Survival rat; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tumor respons; | — |
Countries
China
Contacts
Public ContactShanwen Zhang
Outcome results
None listed