Randomized controlled study about the influence of postoperative use of GnRHa on recurrence and pregnancy rate in moderate or severe endometriosis

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-08000068

Enrollment

Unknown

Registered

2008-03-19

Start date

2008-03-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis

Interventions

Group A:No intervention. Begin spontaneous pregnancy immediately after inclusion

Group B:GnRHa (Zoladex) for 6 courses of treatment, then begin spontaneous pregnancy

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >18 years old; 2. Regular menstruation for 3 months before inclusion; 3. Diagnosed as moderate or severe endometriosis (Stage III-IV) by laparotomy or laparoscopic operation; 4. No obstruction of oviduct; normal semen examination of the husbands; 5. No hormonotherapy before; 6. No participating in other drugs trials within latest 6 months.

Exclusion criteria

Exclusion criteria: 1. Combined with severe diseases of heart, lung, liver or kidney; 2. Malignant change of endometriosis; 3. Abnormal coagulation function; 4. Pregnant or breast-feeding women; 5. Allergic or no response to GnRHa.

Design outcomes

Primary

Measure	Time frame
Recurrence rate;	—

Secondary

Measure	Time frame
Pregnancy rate;	—

Countries

China

Contacts

Public ContactXinmei Zhang

zhangxinm@zju.edu.cn+86 0571 87061501-2131

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026