A randomized controlled trial of Selective Decongestive Devascularization Shunt of Gastrosplenic Region and Pericardial Devascularization with Splenectomy in the treatment of portal hypertension

A randomized controlled trial of SDDS-GSR and PCDV in the treatment of portal hypertension

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-08000041

Enrollment

Unknown

Registered

2008-01-23

Start date

2007-12-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Portal hypertension due to liver cirrhosis

Interventions

Group 1:SDDS-GSR operation

Group 2:PCDV operation

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Diagnostic Criteria: Decompensation Stage due to liver cirrhosis and Child A or B on Child-pugh grading system; 2. Anatomy Requirement: The diameters of splenic vein exceeding 1.0cm, and left renal vein exceeding 0.8cm detected by Doppler US or MRI of portal venous system. No thrombosis in portal system; no hepatofugal flow in portal vein.

Exclusion criteria

Exclusion criteria: 1. Undefined diagnosis; 2. Local anatomic condition is too poor to fit.

Design outcomes

Primary

Measure	Time frame
Incidence of serious complications;Blood dynamic indicators of post-operation;Difference between free portal vein pressure before operation and mesenteric area presure after operation;Quality of life after operation;	—

Secondary

Measure	Time frame
Blood transfusion requirement;Liver function;	—

Countries

China

Contacts

Public ContactQiyu Zhang

zqy80@163.com+86 0 13905775052

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026