Research on the effect of statins on constriction and conposition of coronary atheromatous plaque

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-07000058

Enrollment

Unknown

Registered

2007-09-18

Start date

2007-09-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary heart disease

Interventions

Fluvastatin group:Fluvastatin 80mg every night, oral intake

Atorvastatin group:Atorvastatin 20mg every night, oral intake

Eligibility

Sex/Gender

All

Age

30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age from 30~75 and at least have one vessel with 20%~50% extent of coronary stenosis (not PCI target vessel) and the length of target vessel is more than 30mm; 2. LDL-C range from 125~210mg/dl in basic state.

Exclusion criteria

Exclusion criteria: 1. CAG suggests serious calcification and distortion; 2. Plaque locates in the entrance, distal part and venous bridge of coronary artery; 3. Three vessels with serious pathological changes need complete revascularization; 4. Myocardial infarction in acute phase and malignant tumor, malignant hematological disease and autoimmune disorder; 5. Severe liver disease, alleric to statins and other contraindications; 6. Pregnant or breast-feeding women.

Design outcomes

Primary

Measure	Time frame
Composition and volume of plaque;Cardiovascular events;	—

Secondary

Measure	Time frame
Serum marker;	—

Countries

China

Contacts

Public ContactShaoliang Chen

chmengx@126.com+86 025 52271350

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026