stable angina
Conditions
Interventions
PCI group:stenting with CYPHER DES, combined with loading dosage of antiplatelet agents at least 1 year (according to international standard) and intensive lipid-lowing therapy (according to the inter
medication group:the same treatment protocol as PCI group on antiplatelet treatment and intensive lipid-lowing therapy
Sponsors
Cardiovascular Institute & Fuwai Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Males and no pregnancy women who older than 18 and younger than 75; 2. Patients with stable angina; 3. Coronary arteriography shows that diameter stenosis of de novo lesion is from 50 to 70 percent by visual; 4. Target artery calibre >2.25mm <4.0mm; 5. The minimum lumen from 3.8mm2 to 4.8mm2 detected by intravascular ultrasound (IVUS).
Exclusion criteria
Exclusion criteria: 1. Bifurcation, coronary artery bypass graft, restenosis, severe calcification and left main coronary artery lesions; 2. The sign of plaque rupture, such as partial filling defect indicate thrombosis, or contrast medium retention, ulcer lesion; 3. Patients with acute coronary syndrome; 4. According to borderline lesion which has been infarction-related artery or multi-vessele borderline lesion; 5. The minimum lumen area is less than 3.8mm2 undergoing IVUS measurement will rule out, but PCI should perform; 6. Patient with central neural organic disease; 7. Patient with severe renal or liver function deficiency; 8. Be sensitive to or a confirmed history of intolerance to aspirin or clopidogrel; 9. Patient with malignant tumors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| index of lumen and plaque by QCA and IVUS;Rate of TLR, TVR, Restenosis and Thrombosis;Rate of Major Adverse Cardiac Event (MACE) at different time point; | — |
Countries
China
Contacts
Public ContactChen Jilin
Outcome results
None listed