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Prospective randomized evaluation of the benefits of combining thoracic paravertebral block with general anesthesia in patients undergoing major breast cancer surgery.

Prospective randomized evaluation of the benefits of combining thoracic paravertebral block with general anesthesia in patients undergoing major breast cancer surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-06000687
Enrollment
Unknown
Registered
2006-04-12
Start date
2001-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

Two groups:Single-shot thoracic paravertebral block in conjunction with general anaesthesia versus Only standardaized General anaesthesia with no paraverterbal injection

Sponsors

None listed

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: All consenting adult ASA 1-3 patients under the age of 75 years undergoing major breast cancer surgery will be recruited for this study.

Exclusion criteria

Exclusion criteria: 1. Patients with a known allergy to local anaesthetic drugs; 2. Patient with infection at the site of block placement; 3. Patient with a bleeding tendency or with evidence of coagulopathy; 4. Patient with pre-existing neurological or muscular disorders; 5. Patient with history of psychiatric illness; 6. Pregnant patients; 7. Patients with pre-existing nausea or vomiting; 8. Patients who in the 24 h before surgery received opioids or drugs with antiemetic properties.

Design outcomes

Primary

MeasureTime frame
Postoperative nausea and vomiting;—

Secondary

MeasureTime frame
Postoperative pain, spirometry (FVC, FEV1 and PEFR);—

Countries

China

Contacts

Public ContactProf. Manoj K Karmakar
karmakar@cuhk.edu.hkNil

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026