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Prospective Randomized Evaluation of the Quality of Recovery after Major Breast cancer Surgery in patients reciving either total intravenous anesthesia (TIVA) or thoracic epidural anesthesia.

Prospective Randomized Evaluation of the Quality of Recovery after Major Breast cancer Surgery in patients reciving either total intravenous anesthesia (TIVA) or thoracic epidural anesthesia.

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-06000686
Enrollment
Unknown
Registered
2006-04-12
Start date
2002-09-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast surgery

Interventions

Two groups:Total intravenous Anaesthesia or Thoraci epidural anaesthesia versus Thoracic epidural anaesthesia and Total intravenous anaesthesia

Sponsors

Department of Anaesthesia and Intensive Care, CUHK
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: All consenting adult ASA 1-3 patients under the age of 75 years undergoing major breast cancer surgery will be recruited for this study.

Exclusion criteria

Exclusion criteria: 1. Patients with a known allergy to local anaesthetic drugs; 2. Local infection at or in the vicinity of the epidural catheter placement; 3. Patient with a bleeding tendency or with evidence of coagulopathy; 4. Patient with pre-exiting neurological or muscular disorders; 5. Patients with spinal deformities; 6. Patient with history of psychiatric illness; 7. Patient with history of chronic pain; 8. Patients with a history of significant cardiovascular, respiratory or gastrointestinal disease; 9. Pregnant patients; 10. Patients with pre-existing nausea or vomiting; 11. Patients who in the 24 h prior to surgery had received opioids or drugs with antiemetic properties.

Design outcomes

Primary

MeasureTime frame
Quality of Recovery Score;

Secondary

MeasureTime frame
Post operative pain score, incidence of nausea and vomiting, analgesic requirement;

Countries

China

Contacts

Public ContactManoj K Karmakar
karmakar@cuhk.edu.hkNil

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026