Eye Diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. Age of at least 18 years; 2. Visual acuity 20/50 or poorer; 3. Macular edema of at least 250µm involving the fovea, as documented on optical coherent tomogram; 4. Patients with best corrected visual acuity of better than 1.7 ETDRS logMar units; 5. Patients physically fit to receive laser photocoagulation or intravitreal injection; 6. Informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria 1. Previous photocoagulation for retinal vascular disease of study eye; 2. Intercurrent eye disease except cataract and refractive error that is likely to affect visual acuity over study period; 3. Glaucoma and history of ocular hypertension; 4. Presence of peripheral anterior synechia in the study case; 5. Media opacities which affect fundus examination or OCT measurements; 6. Previous intraocular surgery except uncomplicated cataract extraction and posterior intraocular lens insertion; 7. Any cataract extraction or laser procedure within 3 months; 8. Pregnant patients; 9. Failure to comply with follow up schedule
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best-corrected visual acuity (ETDRS chart); | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Macular edema 2. Intraocular pressure 3. Degree of cataract assessed clinically 4. To measure the level of vascular endothelial growth factor in the vitreous at the time of treatment; | — |
Countries
China