Eye Diseases
Conditions
Interventions
Two groups:Cataract extraction 30 to 45 minutes versus Trabeculectomy
Sponsors
None listed
Eligibility
Sex/Gender
Male
Age
50 Years to 90 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria 1. Eyes with CACG as defined above 2. No significant cataract: VA better than 20/40, and not affecting activities of daily living 3. Patient able and willing to give informed consent to phacoemulsification or trabeculectomy, prior to randomization
Exclusion criteria
Exclusion criteria: Exclusion criteria 1. Single functional eye 2. Eyes with very advanced glaucomatous damage, defined as visual field loss threatening fixation, or cup-to-disc ratio of 0.9 and above 3. Patients refusing either cataract extraction or trabeculectomy 4. Previous intraocular surgery, with the exception of laser peripheral iridotomy and argon laser peripheral iridoplasty (ALPI).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IOP; | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Number of IOP-lowering medications;2. Anesthetic method required, anesthetic complications, and subjective pain score by visual-analog scale;3. Peri-operative complications;4. Operative time, and Total operative time (including second-staged trabeculectomy performed for phaco-alone patients whose IOP is not sufficiently controlled, any other additional glaucoma procedures to further control IOP, and any procedures to handle complications of surgery);5. Visual acuity (VA);6. Angle status by indentation gonioscopy and ultrasound biomicroscopy (UBM);7. Change in visual field by automated perimetry (Humphrey's);8. Change in vertical cup-to-disc ratio of the optic nerve head;9. Rate of aqueous outflow by pneumatonometer measurements;10. Quality of Life (QOL);11. Cost-effective analysis - including any additional procedures required to control IOP and cost of glaucoma drugs; | — |
Countries
China
Contacts
Public ContactProf. Clement CY Tham
Outcome results
None listed