Eye Diseases
Conditions
Interventions
Two groups:Cataract extraction by Phacoemulsification vs Combined Phaco-trabeculectomy for 30 to 45 min
Sponsors
None listed
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: 1. Eyes with CACG and coexisting cataract as defined above; 2. Patient able and willing to give informed consent to phacoemulsification or phaco-TBx, prior to randomization.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. Single functional eye; 2. Eyes with very advanced glaucomatous damage, defined as visual field loss threatening fixation, or cup-to-disc ratio of 0.9 and above; 3. Patients refusing either cataract extraction or trabeculectomy; 4. Previous intraocular surgery, with the exception of laser peripheral iridotomy and argon laser peripheral iridoplasty (ALPI).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IOP; | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Number of IOP-lowering medications;2. Anesthetic method required, anesthetic complications, and subjective pain score by visual-analog scale;3. Peri-operative complications;4. Operative time, and Total operative time (including second-staged trabeculectomy performed for phaco-alone patients whose IOP is not sufficiently controlled, any other additional glaucoma procedures to further control IOP, and any procedures to handle complications of surgery);5. Visual acuity (VA);6. Angle status by indentation gonioscopy and ultrasound biomicroscopy (UBM);7. Change in visual field by automated perimetry (Humphrey's);8. Change in vertical cup-to-disc ratio of the optic nerve head;9. Rate of aqueous outflow by pneumatonometer measurements;10. Quality of Life (QOL);11. Cost-effective analysis - including any additional procedures required to control IOP and cost of glaucoma drugs; | — |
Countries
China
Contacts
Public ContactProf. Clement CY Tham
Outcome results
None listed