Eye Diseases
Conditions
Interventions
Two groups:Photodynamic therapy 24 months vs observation
Sponsors
Nil
Eligibility
Sex/Gender
Male
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: aged 18 years or older; CNV either in the subfoveal or juxtafoveal area Area of CNV = 50% of the area of the total lesion Greatest linear dimension of the entire lesion must not exceed 5400 m Best-corrected visual acuity score of at least 34 letters (Snellen equivalent, approximately 20/200 or better) Understand the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria: Other clinical features suggesting that the CNV may be secondary to the other causes other than pathologic myopia (such as large drusen, geographical atrophy, choroioretinal scar) Tear (rip) of the retinal pigment epithelium Any other significant concurrent ocular diseases in study eye disease that has compromised or could compromise vision in the study eye History of the other prior forms of treatment including photodynamic therapy, laser, surgery Active hepatitis or clinically significant liver disease Porphyria or hypersensitivity/allergy to treatment (fluorescein, verteporfin) Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual acuity; | — |
Secondary
| Measure | Time frame |
|---|---|
| changes in cnv by angiography and optical coherent tomography; | — |
Countries
China
Contacts
Public ContactDr. Timothy Y.Y. Lai
Outcome results
None listed