Study on changes of coagulation and biochemical function in the treatment of subacute liver failure with plasma exchange using FFP or FP

Study on changes of coagulation and biochemical function in the treatment of liver failure with plasma exchange using FFP or FP

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TQR-14004915

Enrollment

Unknown

Registered

2014-05-15

Start date

2014-06-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

subacute liver failure

Interventions

Fresh frozen plasma group and frozen plasma group:exchange plasma with frozen plasma

Eligibility

Sex/Gender

All

Age

6 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients who are diagnosed as subacute liver failure for the first time in our hospital, and recepted the first plasma exchange from July to August in 2014; Patients to be confirmed with lever failure according to the guidelines (2012 edition in China). Aged from 6 to 70 years.

Exclusion criteria

Exclusion criteria: Other types of liver failure; Patients who are not diagnosed as subacute liver failure for the first time in our hospital, and do not recept the first plasma exchange from July to August in 2014; The age is not in the range from 6 to 70.

Design outcomes

Primary

Measure	Time frame
prothrombin time;activated partial thromboplastin time;thrombin time activity;international normalized ratio;fiber fibrinogen;activity levels of coagulation factor F II: C;activity levels of coagulation factor FV: C;activity levels of coagulation factor F VII;total protein;albumin;total bilirubin;direct bilirubin;total bile acid;cholinesterase;creatinin;	—

Countries

China

Contacts

Public ContactFeng Yanqing

Fengyanqing68@sohu.com+86 010-66933357

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026