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A single-center, open label, randomized controlled trial of hypertonic saline vs mannitol to treat the brain edema in acute on chronic liver failure

A single-center, open label, randomized controlled trial of hypertonic saline vs mannitol to treat the brain edema in acute on chronic liver failure

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TQR-13003788
Enrollment
Unknown
Registered
2013-10-14
Start date
2014-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatic encephalopathy

Interventions

hypertonic saline:10%saline
mannitol:20%mannitol

Sponsors

302 Military Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.acute on chronic liver failure with hepatoencephalopathy 3-4 degree.

Exclusion criteria

Exclusion criteria: Miscellaneous cerebral edema other than hepatic encephalopathy. Hemorrhage caused by HCC

Design outcomes

Primary

MeasureTime frame
Mortality;—

Secondary

MeasureTime frame
ICU stay;Duration of ventilator support;—

Countries

China

Contacts

Public ContactLi Ke

302 Military Hospital

keli2004@gmail.com+86 18601199250

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026