The Effects of an Combinedative Treatment of with Prednisone plus and Fluvastatin on the Levels of Cholesterol and Bilirubin in the Patients with Minimal Change Nephropathy

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TQR-12002602

Enrollment

Unknown

Registered

2012-10-16

Start date

2009-10-09

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Minimal change nephrotic syndrome in children

Interventions

Treatment:prednisone 1~2 mg/kg/day+Fluvastatin Sodium Capsule

Control:prednisone 1~2 mg/kg/day

Eligibility

Sex/Gender

All

Age

4 Years to 12 Years

Inclusion criteria

Inclusion criteria: Morphologically normal light microscope glomerular see the swelling of the renal tubular epithelial cells within lipid deposition, electron microscope, epithelial cell swelling, foot processes are widely fusion flattened basement membrane normal. Immunology positive findings. The the Clinical Changbiaoxianwei typical nephrotic syndrome, urinary protein levels greater than 3.5g/24h; plasma albumin content of less than 30g/L, a high degree of swelling, and hyperlipidemia.

Exclusion criteria

Exclusion criteria: Patients with secondary renal disease, or/and glucocorticoid resistance were excluded.

Design outcomes

Primary

Measure	Time frame
TCHO, TG, TBil, Dbil, ALB ;	—

Secondary

Measure	Time frame
Renal biopsy puncture;	—

Countries

China

Contacts

Public ContactMinghui Song

mhso1@sina.com+86 13930300051

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 24, 2026