gastric, colonic or rectal cancer
Conditions
Interventions
Balanced colloid solution therapy:Volume optimization: Three bolus infusion of 3ml/kg of 6% Hydroxyethyl starch 130/40 over 7min Volume maintenance: 6% Hydroxyethyl starch 130/40 at rate of 0.2ml/kg/h
Balanced mixing colloid and crystalloid solution therapy:Volume optimization: Three bolus infusion of 3ml/kg of Ringer’s lactate solution over 7min Volume maintenance: Ringer’s lactate solution at rat
Balanced crystalloid solution therapy:Three bolus infusion of 3ml/kg of 6% Hydroxyethyl starch over 7mins Volume maintenance: Ringer’s lactate solution at rate of 0.2ml/kg/h
Balanced mixing colloid and crystalloid solution therapy:Preloading: 500ml of Ringer’s lactate solution over 2 h, beginning 3 h before induction of anesthesia Volume optimization: Three bolus infusion
Sponsors
the First affiliated Hospital, college of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
25 Years to 75 Years
Inclusion criteria
Inclusion criteria: patients scheduled for elective laparoscopic or open gastrointestinal surgery performed under intravenous general anaesthesia were recruited to participate in the study
Exclusion criteria
Exclusion criteria: Exclusion criteria were liver or renal dysfunction (liver enzymes >50% or serum creatinine >50% of normal), coagulation disturbances, obstructive pulmonary disease (airway pressure >25mmHg), atrial fibrillation, and mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In-hospital post-operative complications of any cause (censored at 30 days following surgery); | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative volume status and haemodynamic response to induction of general anesthesia;Blood volume of efficiency of starch and Ringer solution;Urine index during surgery;Duration of hospital stay after surgery; | — |
Countries
China
Contacts
Public ContactYuhong Li
Shaoxing People's Hospital
Outcome results
None listed