Diagnosed with primary lung cancer (including small cell lung cancer, lung adenocarcinoma, squamous cell carcinoma and large cell carcinoma)
Conditions
Interventions
A:Infusion of umbilical cord blood CIK cells to bes
B:best supportive care
Sponsors
The 105st Hospital of PLA
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) 18 to 75 years, KPS score >=50 points, estimated survival of> 3 months; 2) in primary lung cancer patients after chemotherapy or radiotherapy; 3) in patients with primary lung cancer targeted therapy; 4) do not want to receive chemotherapy or radiotherapy in patients with primary lung cancer; 5) The general condition due to poor lung function can not accept or do not want surgery or surgery of primary lung cancer patients; 6) recurrence after surgery or surgery can not be completely resected primary lung cancer patients; 7) intervention (I125 seed implantation, cryotherapy, radio frequency, etc.) after the primary lung cancer patients; 8) without serious mental illness and no serious heart, liver, kidney, pulmonary insufficiency, not associated with other fatal diseases; 9) voluntary subjects, informed consent.
Exclusion criteria
Exclusion criteria: 1) history of cardiovascular disease: congestive heart failure> New York Heart Association (NYHA) II level, patients with unstable angina (angina symptoms occur at rest) or new onset of angina (the last 3 months of onset) or recent myocardial infarction within 6 months of patients; 2) poor body condition, cachexia;Or in combination with other fatal diseases; 3) laboratory tests of liver function ALT, AST 2.0 times higher than the upper limit of normal; Or renal TBIL, Bun more than 1.0 times the upper limit of normal, or Cr above the normal upper limit; 4) active infection; 5) patients pregnant or lactating women; 6) is now open for other anti-cancer therapy (eg chemotherapy, radiotherapy, chemotherapy, embolization and immunosuppressive agents and targeted agents); 7) Now, the recent (-4 weeks, 1 day before) or will join another clinical drug trial research; 8) The researchers believe that other circumstances can not be selected: If the impact into the group of patients to participate in or completion of clinical studies (such as mental illness, substance abuse, HIV infection, etc.), or affect the results of the analysis of clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| short-term effect: disease control rate of DCR (CR + PR SD);Long-term effect: Progression-Free Srvival (PFS);Immune indeces; | — |
Countries
China
Contacts
Public ContactWei Wang
Outcome results
None listed