Peripheral nerve injury in the upper limbs(radial nerve,median nerve,ulna nerve)
Conditions
Interventions
Test group:use acellular nerve graft to bridge the nerve defects
Control group:use nerve autograft or direct suture to bridge the nerve defects.
Sponsors
The Sixth Affiliated Hospital of Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Age
14 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. had radial nerve, median nerve or ulna nerve defects and were willing to participate in this clinical trial; 2. were >14 years of age; 3. had a nerve defect that can be repaired with nerve graft of 2-5 cm in length or required traditional repairs(include nerve autograft or direct suture); 4. the duration of injury was less than 6 months; 5. were willing to sign an informed consent form to receive examinations, treatment, and postoperative follow-up.
Exclusion criteria
Exclusion criteria: 1) patients with acute infections, severe wound contamination, unstable vital signs, or functional assessment of nerve repair could not be performed due to skin damage innervated by the nerve that required repair; 2) patients for whom functional assessment could not be performed due to joint stiffness controlled by the muscles innervated by nerves that required repair; 3) patients with neurological diseases or other diseases such as diabetes that may potentially affect the nervous system; 4) patients with chronic diseases, including gout and collagen disease, alcohol addiction, alcoholism, liver impairment, or renal dysfunction; 5) patients with poor compliance and patients who could not complete examinations, treatment, postoperative rehabilitation, or follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BMRC M0-M5; | — |
Secondary
| Measure | Time frame |
|---|---|
| BMRC S0-S4; | — |
Countries
China
Contacts
Public ContactXiaolin Liu
Outcome results
None listed