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Human acellular nerve graft for repair of pure sensory nerve defects: a prospective, multicenter clinical study

Human acellular nerve graft for repair of pure sensory nerve defects: a prospective, multicenter clinical study

Status
Active, not recruiting
Phases
Phase 3
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR-TNRC-11001443
Enrollment
Unknown
Registered
2011-07-24
Start date
2009-11-04
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

digital nerve injury

Interventions

Test group:using traditional methods(direct suture or autologous nerve graft) to repair pure sensory nerve defects
Control group:using hANG to repair pure sensory nerve defects

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) had pure sensory nerve defects and were willing to participate in this clinical trial (upper limb); 2) were >14 years of age; 3) had a nerve defect that was 1-5 cm in length and required nerve transplantation; 4) the duration of injury was less than 6 months; 5) were willing to sign an informed consent form to receive examinations, treatment, and postoperative follow-up.

Exclusion criteria

Exclusion criteria: 1) patients with acute infections, severe wound contamination, unstable vital signs, or functional assessment of nerve repair could not be performed due to skin damage innervated by the nerve that required repair; 2) patients for whom functional assessment could not be performed due to joint stiffness controlled by the muscles innervated by nerves that required repair; 3) patients with neurological diseases or other diseases such as diabetes that may potentially affect the nervous system; 4) patients with chronic diseases, including gout and collagen disease, alcohol addiction, alcoholism, liver impairment, or renal dysfunction; 5) patients with poor compliance and patients who could not complete examinations, treatment, postoperative rehabilitation, or follow-up.

Design outcomes

Primary

MeasureTime frame
Semmes-Weinstein (SW) monofilament;

Countries

China

Contacts

Public ContactXiaolin Liu
peterhe400@yahoo.com.cn+86 13570506043

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026