Healthy volunteers
Conditions
Interventions
CYP2B6*6/*6:CYP2B6*6/*6
CYP2B6*1/*1:CYP2B6*1/*1
CYP2B6*1/*6:CYP2B6*1/*6
Sponsors
Pharmacogenetics Research Institute, Institute of Clinical Pharmacology, Central South University
Eligibility
Sex/Gender
Male
Age
18 Years to 23 Years
Inclusion criteria
Inclusion criteria: 1. Male 18 years old and over; 2. The subjects were ascertained to be in good health by medical history, a full clinical examination, and standard hematologic and blood chemistry laboratory tests before enrollment; 3. The subjects were not taking any regular medication and were asked to refrain from consuming alcohol, grapefruit juice, coffee, green tea, any vitamins and nutritional supplements for 2 weeks before study commencement and throughout the study.
Exclusion criteria
Exclusion criteria: 1. Check the indicators are not normal; 2. smokers or drinkers; 3. taking other drugs in two weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bupropion AUC0-infinity;Bupropion AUC0-48; | — |
Countries
China
Contacts
Public ContactLan Fan
Outcome results
None listed