Endometrial carcinoma (early-stage )
Conditions
Interventions
Group A:Segmental tylectomy under hysteroscope + consolidation therapy of highly active progesterone
Group B:Hysterosalpingo-oophorectomy
Sponsors
Beijing Obstetrics and Gynecology Hospital, Capital Medical University hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. With the informed consent signed; 2. Females age 18-40 years strongly wish for the fertility and refuse the complete hysterectomy; 3. Carcinoma is limited in the uterine cavity under the hysteroscope; 4. Tumor infiltration <1/2 and without pelvic metastasis detected by pelvic B ultrasound or MRI; 5. Serum CA125 is normal and <35KU/L.
Exclusion criteria
Exclusion criteria: 1. Complicated with cardiovascular, hepartic, renal and hematopoietic disease or other malignant tumor; 2. With poor compliance and difficult to follow-up; 4. Participating in other trials at the same time; 5. Other conditions improper for the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease-free survival;Five-year survival rate;Complications in and after surgery;Pregnancy rate after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Average operation time, bleeding volume; | — |
Countries
China
Contacts
Public ContactHua Duan
Outcome results
None listed